Сравнение

Glepaglutide vs. Semax

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Исследования (прочее)

Номер CAS

нет данных

80714-61-0

Молекулярная масса

нет данных

813.92 g/mol

Период полувыведения

нет данных

0.3 h

Последовательность

нет данных

Met-Glu-His-Phe-Pro-Gly-Pro

Механизм действия

Glepaglutide

As a GLP-2 receptor agonist, glepaglutide has a trophic effect on the intestinal mucosa, enlarging the absorptive surface and thereby improving intestinal uptake of nutrients and fluid.

Semax

Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.

Доказательная база

Наивысшая доказательность

РКИ на людях

Исследование на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	Glepaglutide	Semax
Германия	Не одобрено	Не одобрено
RU	—	Рецептурный
США	Не одобрено	Не одобрено

Полные записи

Frequently asked questions

What is the difference between Glepaglutide and Semax?: Glepaglutide is classified as "Исследования (прочее)", while Semax is classified as "Исследования (прочее)". Glepaglutide: Glepaglutide is a long-acting GLP-2 analogue (Zealand Pharma) intended to reduce the need for parenteral support in short bowel syndrome. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Glepaglutide or Semax?: The highest available evidence level is "РКИ на людях" for Glepaglutide and "Исследование на людях" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Glepaglutide and Semax in Germany and the United States?: Германия: Glepaglutide — Не одобрено, Semax — Не одобрено. США: Glepaglutide — Не одобрено, Semax — Не одобрено. These are factual summaries with source and review date on the individual pages.

Country

Glepaglutide

Semax

Германия

Не одобрено

—

Рецептурный

США

Не одобрено

Frequently asked questions

What is the difference between Glepaglutide and Semax?

Glepaglutide is classified as "Исследования (прочее)", while Semax is classified as "Исследования (прочее)". Glepaglutide: Glepaglutide is a long-acting GLP-2 analogue (Zealand Pharma) intended to reduce the need for parenteral support in short bowel syndrome. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Glepaglutide or Semax?

The highest available evidence level is "РКИ на людях" for Glepaglutide and "Исследование на людях" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Glepaglutide and Semax in Germany and the United States?

Германия: Glepaglutide — Не одобрено, Semax — Не одобрено. США: Glepaglutide — Не одобрено, Semax — Не одобрено. These are factual summaries with source and review date on the individual pages.