Сравнение
Histrelin vs. Selank
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
220810-26-4
129954-34-3
Молекулярная масса
1323.52 g/mol
751.85 g/mol
Период полувыведения
нет данных
0.3 h
Последовательность
нет данных
Thr-Lys-Pro-Arg-Pro-Gly-ProМеханизм действия
Histrelin
Continuous GnRH-agonist stimulation downregulates and desensitises the pituitary GnRH receptors — after the initial rise, LH, FSH and the sex hormones fall persistently.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Доказательная база
Наивысшая доказательность
РКИ на людях
Исследование на людях
Исследования
0
4
из них на людях
0
2
Зафиксированные эффекты
2
3
Открытые противоречия
0
1
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Histrelin and Selank?
- Histrelin is classified as "Исследования (прочее)", while Selank is classified as "Исследования (прочее)". Histrelin: Histrelin is a nonapeptide GnRH agonist delivered as a once-yearly implant. Approved for central precocious puberty in children (Supprelin LA) and advanced prostate cancer (Vantas). Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Histrelin or Selank?
- The highest available evidence level is "РКИ на людях" for Histrelin and "Исследование на людях" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Histrelin and Selank in Germany and the United States?
- Германия: Histrelin — Рецептурный, Selank — Не одобрено. США: Histrelin — Рецептурный, Selank — Не одобрено. These are factual summaries with source and review date on the individual pages.