Сравнение

Melanotan II vs. Sekretin

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Исследования (прочее)

Номер CAS

121062-08-6

нет данных

Молекулярная масса

1024.18 g/mol

3055.5 g/mol

Период полувыведения

1 h

нет данных

Последовательность

Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

нет данных

Механизм действия

Melanotan II

Melanotan II binds non-selectively to all five melanocortin-receptor subtypes (MC1R-MC5R). Via MC1R in melanocytes, eumelanin synthesis is stimulated (pigmenting effect). Via MC4R and MC3R in the CNS, appetite, sexual function and blood pressure are modulated. The cyclic structure and D-amino acids increase stability compared to natural α-MSH.

Sekretin

Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.

Доказательная база

Наивысшая доказательность

Исследование на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	Melanotan II	Sekretin
Австралия	Запрещено	—
Германия	Не одобрено	Рецептурный
Великобритания	Запрещено	—
США	Не одобрено	Рецептурный

Полные записи

Frequently asked questions

What is the difference between Melanotan II and Sekretin?: Melanotan II is classified as "Исследования (прочее)", while Sekretin is classified as "Исследования (прочее)". Melanotan II: Cyclic hepta-peptide and non-selective melanocortin-receptor agonist. Originally researched at the University of Arizona as a sun-protection concept — never approved as a medicine. Widespread on the black market; regulatory warnings for cardiovascular and oncological risks. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Melanotan II or Sekretin?: The highest available evidence level is "Исследование на людях" for Melanotan II and "Исследование на людях" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Melanotan II and Sekretin in Germany and the United States?: Германия: Melanotan II — Не одобрено, Sekretin — Рецептурный. США: Melanotan II — Не одобрено, Sekretin — Рецептурный. These are factual summaries with source and review date on the individual pages.

Country

Melanotan II

Sekretin

Австралия

Запрещено

—

Германия

Не одобрено

Рецептурный

Великобритания

Запрещено

—

США

Не одобрено

Рецептурный

Frequently asked questions

What is the difference between Melanotan II and Sekretin?

Melanotan II is classified as "Исследования (прочее)", while Sekretin is classified as "Исследования (прочее)". Melanotan II: Cyclic hepta-peptide and non-selective melanocortin-receptor agonist. Originally researched at the University of Arizona as a sun-protection concept — never approved as a medicine. Widespread on the black market; regulatory warnings for cardiovascular and oncological risks. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Melanotan II or Sekretin?

The highest available evidence level is "Исследование на людях" for Melanotan II and "Исследование на людях" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Melanotan II and Sekretin in Germany and the United States?

Германия: Melanotan II — Не одобрено, Sekretin — Рецептурный. США: Melanotan II — Не одобрено, Sekretin — Рецептурный. These are factual summaries with source and review date on the individual pages.