Сравнение
Melanotan II vs. Vasopressin
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
121062-08-6
нет данных
Молекулярная масса
1024.18 g/mol
1084.23 g/mol
Период полувыведения
1 h
нет данных
Последовательность
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2нет данных
Механизм действия
Melanotan II
Melanotan II binds non-selectively to all five melanocortin-receptor subtypes (MC1R-MC5R). Via MC1R in melanocytes, eumelanin synthesis is stimulated (pigmenting effect). Via MC4R and MC3R in the CNS, appetite, sexual function and blood pressure are modulated. The cyclic structure and D-amino acids increase stability compared to natural α-MSH.
Vasopressin
Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
9
0
из них на людях
5
0
Зафиксированные эффекты
4
2
Открытые противоречия
1
0
Задокументированные нежелательные явления
6
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Melanotan II and Vasopressin?
- Melanotan II is classified as "Исследования (прочее)", while Vasopressin is classified as "Исследования (прочее)". Melanotan II: Cyclic hepta-peptide and non-selective melanocortin-receptor agonist. Originally researched at the University of Arizona as a sun-protection concept — never approved as a medicine. Widespread on the black market; regulatory warnings for cardiovascular and oncological risks. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Melanotan II or Vasopressin?
- The highest available evidence level is "Исследование на людях" for Melanotan II and "РКИ на людях" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Melanotan II and Vasopressin in Germany and the United States?
- Германия: Melanotan II — Не одобрено, Vasopressin — Рецептурный. США: Melanotan II — Не одобрено, Vasopressin — Рецептурный. These are factual summaries with source and review date on the individual pages.