Сравнение

Sekretin vs. Semax

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Исследования (прочее)

Номер CAS

нет данных

80714-61-0

Молекулярная масса

3055.5 g/mol

813.92 g/mol

Период полувыведения

нет данных

0.3 h

Последовательность

нет данных

Met-Glu-His-Phe-Pro-Gly-Pro

Механизм действия

Sekretin

Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.

Semax

Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.

Доказательная база

Наивысшая доказательность

Исследование на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	Sekretin	Semax
Германия	Рецептурный	Не одобрено
RU	—	Рецептурный
США	Рецептурный	Не одобрено

Полные записи

Frequently asked questions

What is the difference between Sekretin and Semax?: Sekretin is classified as "Исследования (прочее)", while Semax is classified as "Исследования (прочее)". Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Sekretin or Semax?: The highest available evidence level is "Исследование на людях" for Sekretin and "Исследование на людях" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Sekretin and Semax in Germany and the United States?: Германия: Sekretin — Рецептурный, Semax — Не одобрено. США: Sekretin — Рецептурный, Semax — Не одобрено. These are factual summaries with source and review date on the individual pages.

Country

Sekretin

Semax

Германия

Рецептурный

Не одобрено

—

Рецептурный

США

Рецептурный

Не одобрено

Frequently asked questions

What is the difference between Sekretin and Semax?

Sekretin is classified as "Исследования (прочее)", while Semax is classified as "Исследования (прочее)". Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Sekretin or Semax?

The highest available evidence level is "Исследование на людях" for Sekretin and "Исследование на людях" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Sekretin and Semax in Germany and the United States?

Германия: Sekretin — Рецептурный, Semax — Не одобрено. США: Sekretin — Рецептурный, Semax — Не одобрено. These are factual summaries with source and review date on the individual pages.