Сравнение
Semaglutid vs. VK2735
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Метаболизм
Метаболизм
Номер CAS
910463-68-2
нет данных
Молекулярная масса
4113.6 g/mol
нет данных
Период полувыведения
165 h
нет данных
Последовательность
modifiziertes GLP-1-Analogon (31 AS) mit C18-Fettsäure-Linkerнет данных
Механизм действия
Semaglutid
Long-acting agonist at the GLP-1 receptor. Structurally a modified glucagon-like peptide 1 whose long half-life is achieved via a fatty-acid side chain and reversible albumin binding. Acts centrally on satiety and peripherally on glucose-dependent insulin secretion and delayed gastric emptying.
VK2735
VK2735 activates both the GLP-1 and the GIP receptor — a dual mechanism similar to that of tirzepatide, suppressing appetite and food intake.
Доказательная база
Наивысшая доказательность
РКИ на людях
РКИ на людях
Исследования
4
1
из них на людях
3
1
Зафиксированные эффекты
3
2
Открытые противоречия
1
0
Задокументированные нежелательные явления
5
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Semaglutid and VK2735?
- Semaglutid is classified as "Метаболизм", while VK2735 is classified as "Метаболизм". Semaglutid: Long-acting GLP-1 receptor agonist. Approved as a medicinal product for type-2 diabetes (Ozempic, Rybelsus), chronic weight management (Wegovy) and cardiovascular risk in obesity. One of the best-studied substances on this platform — many large human RCTs. VK2735: VK2735 is a dual GLP-1/GIP receptor agonist from Viking Therapeutics, in development in both subcutaneous and oral forms for obesity. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Semaglutid or VK2735?
- The highest available evidence level is "РКИ на людях" for Semaglutid and "РКИ на людях" for VK2735. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Semaglutid and VK2735 in Germany and the United States?
- Германия: Semaglutid — Рецептурный, VK2735 — Не одобрено. США: Semaglutid — Рецептурный, VK2735 — Не одобрено. These are factual summaries with source and review date on the individual pages.