Confronto

Cetrorelix vs. Semax

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Ricerca (altro)

N. CAS

120287-85-6

80714-61-0

Peso molecolare

1431.06 g/mol

813.92 g/mol

Emivita

nessun dato

0.3 h

Sequenza

nessun dato

Met-Glu-His-Phe-Pro-Gly-Pro

Meccanismo d'azione

Cetrorelix

Cetrorelix competitively and immediately blocks the pituitary GnRH receptor, rapidly suppressing LH and FSH release — without the initial hormone surge ('flare') of GnRH agonists.

Semax

Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.

Base di evidenze

Evidenza più alta

RCT sull'uomo

Studio sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Cetrorelix	Semax
Germania	Su prescrizione	Non approvato
RU	—	Su prescrizione
Stati Uniti	Su prescrizione	Non approvato

Voci complete

Frequently asked questions

What is the difference between Cetrorelix and Semax?: Cetrorelix is classified as "Ricerca (altro)", while Semax is classified as "Ricerca (altro)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Cetrorelix or Semax?: The highest available evidence level is "RCT sull'uomo" for Cetrorelix and "Studio sull'uomo" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Cetrorelix and Semax in Germany and the United States?: Germania: Cetrorelix — Su prescrizione, Semax — Non approvato. Stati Uniti: Cetrorelix — Su prescrizione, Semax — Non approvato. These are factual summaries with source and review date on the individual pages.

Country

Cetrorelix

Semax

Germania

Su prescrizione

Non approvato

—

Su prescrizione

Stati Uniti

Su prescrizione

Non approvato

Frequently asked questions

What is the difference between Cetrorelix and Semax?

Cetrorelix is classified as "Ricerca (altro)", while Semax is classified as "Ricerca (altro)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Cetrorelix or Semax?

The highest available evidence level is "RCT sull'uomo" for Cetrorelix and "Studio sull'uomo" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Cetrorelix and Semax in Germany and the United States?

Germania: Cetrorelix — Su prescrizione, Semax — Non approvato. Stati Uniti: Cetrorelix — Su prescrizione, Semax — Non approvato. These are factual summaries with source and review date on the individual pages.