Сравнение
Cetrorelix vs. DSIP
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
120287-85-6
62568-57-4
Молекулярная масса
1431.06 g/mol
848.81 g/mol
Период полувыведения
нет данных
0.1 h
Последовательность
нет данных
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-GluМеханизм действия
Cetrorelix
Cetrorelix competitively and immediately blocks the pituitary GnRH receptor, rapidly suppressing LH and FSH release — without the initial hormone surge ('flare') of GnRH agonists.
DSIP
DSIP was described in 1977 by the Schoenenberger-Monnier group in Basel as a blood-borne substance reported to induce EEG changes similar to delta sleep in animal models. The exact mechanism remains undefined to this day: no defined receptor, proposed modulation of opioid, GABAergic and glutamatergic systems. Most mechanistic findings stem from preclinical studies of the 1980s and 1990s and were later subjected to contested replication attempts.
Доказательная база
Наивысшая доказательность
РКИ на людях
Исследование на людях
Исследования
0
4
из них на людях
0
1
Зафиксированные эффекты
2
3
Открытые противоречия
0
1
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Cetrorelix and DSIP?
- Cetrorelix is classified as "Исследования (прочее)", while DSIP is classified as "Исследования (прочее)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. DSIP: Synthetic nonapeptide isolated in 1977 by Guido Monnier and Marcel Schoenenberger from the blood of rabbits in delta sleep. Despite the name, the role in sleep regulation is contested and not confirmed by Western RCTs in larger populations. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Cetrorelix or DSIP?
- The highest available evidence level is "РКИ на людях" for Cetrorelix and "Исследование на людях" for DSIP. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Cetrorelix and DSIP in Germany and the United States?
- Германия: Cetrorelix — Рецептурный, DSIP — Не одобрено. США: Cetrorelix — Рецептурный, DSIP — Не одобрено. These are factual summaries with source and review date on the individual pages.