Сравнение
Lanreotid vs. Semax
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
108736-35-2
80714-61-0
Молекулярная масса
1096.34 g/mol
813.92 g/mol
Период полувыведения
нет данных
0.3 h
Последовательность
нет данных
Met-Glu-His-Phe-Pro-Gly-ProМеханизм действия
Lanreotid
Lanreotide activates somatostatin receptors (chiefly SSTR2, additionally SSTR5), thereby suppressing the release of growth hormone, IGF-1 and various gastrointestinal and neuroendocrine hormones. It is metabolically far more stable than natural somatostatin.
Semax
Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.
Доказательная база
Наивысшая доказательность
РКИ на людях
Исследование на людях
Исследования
1
4
из них на людях
1
2
Зафиксированные эффекты
2
3
Открытые противоречия
1
1
Задокументированные нежелательные явления
2
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Lanreotid and Semax?
- Lanreotid is classified as "Исследования (прочее)", while Semax is classified as "Исследования (прочее)". Lanreotid: Lanreotide is a synthetic cyclic octapeptide analog of somatostatin. It binds preferentially to the somatostatin receptors SSTR2 and SSTR5 and is approved for treating acromegaly and certain neuroendocrine tumours. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Lanreotid or Semax?
- The highest available evidence level is "РКИ на людях" for Lanreotid and "Исследование на людях" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Lanreotid and Semax in Germany and the United States?
- Германия: Lanreotid — Рецептурный, Semax — Не одобрено. США: Lanreotid — Рецептурный, Semax — Не одобрено. These are factual summaries with source and review date on the individual pages.