Vergelijking
Lanreotid vs. Semax
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
108736-35-2
80714-61-0
Molecuulmassa
1096.34 g/mol
813.92 g/mol
Halfwaardetijd
geen gegevens
0.3 h
Sequentie
geen gegevens
Met-Glu-His-Phe-Pro-Gly-ProWerkingsmechanisme
Lanreotid
Lanreotide activates somatostatin receptors (chiefly SSTR2, additionally SSTR5), thereby suppressing the release of growth hormone, IGF-1 and various gastrointestinal and neuroendocrine hormones. It is metabolically far more stable than natural somatostatin.
Semax
Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane studie
Studies
1
4
waarvan bij mensen
1
2
Geregistreerde effecten
2
3
Openstaande tegenstrijdigheden
1
1
Gedocumenteerde bijwerkingen
2
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Lanreotid and Semax?
- Lanreotid is classified as "Onderzoek (overig)", while Semax is classified as "Onderzoek (overig)". Lanreotid: Lanreotide is a synthetic cyclic octapeptide analog of somatostatin. It binds preferentially to the somatostatin receptors SSTR2 and SSTR5 and is approved for treating acromegaly and certain neuroendocrine tumours. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Lanreotid or Semax?
- The highest available evidence level is "Humane RCT" for Lanreotid and "Humane studie" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Lanreotid and Semax in Germany and the United States?
- Duitsland: Lanreotid — Op recept, Semax — Niet goedgekeurd. Verenigde Staten: Lanreotid — Op recept, Semax — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.