Сравнение

Terlipressin vs. Vasopressin

Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.

Идентичность

Категория

Исследования (прочее)

Номер CAS

14636-12-5

нет данных

Молекулярная масса

1227.37 g/mol

1084.23 g/mol

Период полувыведения

нет данных

Последовательность

нет данных

Механизм действия

Terlipressin

Terlipressin is slowly converted in the body to lysine-vasopressin by cleavage of the three N-terminal glycyl residues (reservoir effect) and activates V1 receptors. The splanchnic vasoconstriction improves renal perfusion in hepatorenal syndrome.

Vasopressin

Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.

Доказательная база

Наивысшая доказательность

РКИ на людях

Исследования

из них на людях

Зафиксированные эффекты

Открытые противоречия

Задокументированные нежелательные явления

Правовой статус

Country	Terlipressin	Vasopressin
Германия	Рецептурный	Рецептурный
США	Рецептурный	Рецептурный

Полные записи

Frequently asked questions

What is the difference between Terlipressin and Vasopressin?: Terlipressin is classified as "Исследования (прочее)", while Vasopressin is classified as "Исследования (прочее)". Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Terlipressin or Vasopressin?: The highest available evidence level is "РКИ на людях" for Terlipressin and "РКИ на людях" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Terlipressin and Vasopressin in Germany and the United States?: Германия: Terlipressin — Рецептурный, Vasopressin — Рецептурный. США: Terlipressin — Рецептурный, Vasopressin — Рецептурный. These are factual summaries with source and review date on the individual pages.

Country

Terlipressin

Vasopressin

Германия

Рецептурный

США

Рецептурный

Frequently asked questions

What is the difference between Terlipressin and Vasopressin?

Terlipressin is classified as "Исследования (прочее)", while Vasopressin is classified as "Исследования (прочее)". Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Terlipressin or Vasopressin?

The highest available evidence level is "РКИ на людях" for Terlipressin and "РКИ на людях" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Terlipressin and Vasopressin in Germany and the United States?

Германия: Terlipressin — Рецептурный, Vasopressin — Рецептурный. США: Terlipressin — Рецептурный, Vasopressin — Рецептурный. These are factual summaries with source and review date on the individual pages.