Vergelijking

Terlipressin vs. Vasopressin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

14636-12-5

geen gegevens

Molecuulmassa

1227.37 g/mol

1084.23 g/mol

Halfwaardetijd

geen gegevens

Sequentie

geen gegevens

Werkingsmechanisme

Terlipressin

Terlipressin is slowly converted in the body to lysine-vasopressin by cleavage of the three N-terminal glycyl residues (reservoir effect) and activates V1 receptors. The splanchnic vasoconstriction improves renal perfusion in hepatorenal syndrome.

Vasopressin

Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.

Bewijsbasis

Hoogste bewijs

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Terlipressin	Vasopressin
Duitsland	Op recept	Op recept
Verenigde Staten	Op recept	Op recept

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Terlipressin

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Vasopressin

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Frequently asked questions

What is the difference between Terlipressin and Vasopressin?: Terlipressin is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Terlipressin or Vasopressin?: The highest available evidence level is "Humane RCT" for Terlipressin and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Terlipressin and Vasopressin in Germany and the United States?: Duitsland: Terlipressin — Op recept, Vasopressin — Op recept. Verenigde Staten: Terlipressin — Op recept, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Terlipressin

Vasopressin

Duitsland

Op recept

Verenigde Staten

Op recept

Frequently asked questions

What is the difference between Terlipressin and Vasopressin?

Terlipressin is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Terlipressin or Vasopressin?

The highest available evidence level is "Humane RCT" for Terlipressin and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Terlipressin and Vasopressin in Germany and the United States?

Duitsland: Terlipressin — Op recept, Vasopressin — Op recept. Verenigde Staten: Terlipressin — Op recept, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.