Confronto
CJC-1295 vs. Ipamorelin
Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.
Identità
Categoria
Crescita
Crescita
N. CAS
nessun dato
170851-70-4
Peso molecolare
3647.3 g/mol
711.86 g/mol
Emivita
144 h
2 h
Sequenza
YADAIFTNSYRKVLGQLSARKLLQDIMSR-DACAib-His-D-2-Nal-D-Phe-Lys-NH2Meccanismo d'azione
CJC-1295
Synthetic analogue of growth-hormone-releasing hormone (GHRH), modified for extended half-life via a Drug Affinity Complex (DAC) binding to albumin. Acts on the pituitary GHRH receptor and stimulates endogenous growth-hormone release.
Ipamorelin
Ipamorelin is a selective agonist at the GH secretagogue receptor (GHSR-1a). Compared to GHRP-2 and GHRP-6 its selectivity for the growth-hormone axis is higher; ACTH, cortisol and prolactin are not significantly stimulated in clinical studies. This selectivity was the main reason for its development over older GHRPs.
Base di evidenze
Evidenza più alta
Studio sull'uomo
RCT sull'uomo
Studi
4
4
di cui sull'uomo
3
3
Effetti registrati
3
3
Contraddizioni aperte
1
1
Eventi avversi documentati
3
1
Stato legale
Voci complete
Frequently asked questions
- What is the difference between CJC-1295 and Ipamorelin?
- CJC-1295 is classified as "Crescita", while Ipamorelin is classified as "Crescita". CJC-1295: Long-acting synthetic GHRH analogue modified for albumin binding (DAC). Stimulates endogenous growth-hormone release. Pharmacodynamic effect established in small human studies; clinical endpoint trials are missing. Ipamorelin: Synthetic pentapeptide and selective growth-hormone secretagogue. Developed at Novo Nordisk in the 1990s as a pentapeptide GHRP successor; clinical development was discontinued after phase 2 (post-operative ileus). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, CJC-1295 or Ipamorelin?
- The highest available evidence level is "Studio sull'uomo" for CJC-1295 and "RCT sull'uomo" for Ipamorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of CJC-1295 and Ipamorelin in Germany and the United States?
- Germania: CJC-1295 — Non approvato, Ipamorelin — Non approvato. Stati Uniti: CJC-1295 — Solo ricerca, Ipamorelin — Non approvato. These are factual summaries with source and review date on the individual pages.