Confronto
Pasireotid vs. Selank
Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.
Identità
Categoria
Ricerca (altro)
Ricerca (altro)
N. CAS
396091-73-9
129954-34-3
Peso molecolare
1047.21 g/mol
751.85 g/mol
Emivita
nessun dato
0.3 h
Sequenza
nessun dato
Thr-Lys-Pro-Arg-Pro-Gly-ProMeccanismo d'azione
Pasireotid
Pasireotide binds more broadly than older somatostatin analogs (SSTR1/2/3/5) with particularly high affinity for SSTR5. This suppresses, among others, ACTH release in Cushing's disease and GH release in acromegaly.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Base di evidenze
Evidenza più alta
RCT sull'uomo
Studio sull'uomo
Studi
1
4
di cui sull'uomo
1
2
Effetti registrati
2
3
Contraddizioni aperte
0
1
Eventi avversi documentati
2
1
Stato legale
Voci complete
Frequently asked questions
- What is the difference between Pasireotid and Selank?
- Pasireotid is classified as "Ricerca (altro)", while Selank is classified as "Ricerca (altro)". Pasireotid: Pasireotide is a multireceptor somatostatin analog binding to four of the five somatostatin receptors (especially SSTR5). It is approved for Cushing's disease and acromegaly. Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Pasireotid or Selank?
- The highest available evidence level is "RCT sull'uomo" for Pasireotid and "Studio sull'uomo" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Pasireotid and Selank in Germany and the United States?
- Germania: Pasireotid — Su prescrizione, Selank — Non approvato. Stati Uniti: Pasireotid — Su prescrizione, Selank — Non approvato. These are factual summaries with source and review date on the individual pages.