Confronto

Thymalin vs. Thymosin Alpha-1

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Guarigione

N. CAS

63958-90-7

62304-98-7

Peso molecolare

1000 g/mol

3108.32 g/mol

Emivita

0.5 h

2 h

Sequenza

nessun dato

Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN

Meccanismo d'azione

Thymalin

Thymalin is a complex of multiple polypeptides extracted from bovine or calf thymus. Postulated mechanisms include modulation of T-lymphocyte maturation, influence on interleukin profiles and stimulation of cellular immune response. Being a multi-component preparation, individual mechanisms are difficult to disentangle. Khavinson and colleagues from St Petersburg have described the mechanism over decades in Russian publications.

Thymosin Alpha-1

Thymosin Alpha-1 is an N-terminally acetylated peptide originally isolated from the thymus. It modulates T-lymphocyte maturation and function and acts on dendritic cells via Toll-like receptors (TLR9 / TLR2). In preclinical and some clinical studies, increased interferon-gamma responses and altered T-cell subpopulations have been reported.

Base di evidenze

Evidenza più alta

Studio sull'uomo

RCT sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Thymalin	Thymosin Alpha-1
Germania	Non approvato	Non approvato
IT	—	Su prescrizione
RU	Su prescrizione	—
Stati Uniti	Non approvato	Non approvato

Voci complete

Frequently asked questions

What is the difference between Thymalin and Thymosin Alpha-1?: Thymalin is classified as "Guarigione", while Thymosin Alpha-1 is classified as "Guarigione". Thymalin: Complex of low-molecular polypeptides extracted from calf thymus. Approved in Russia since the 1970s as an immunomodulator. The exact composition is not standardised like a synthetic single peptide; Western controlled studies are largely absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Thymalin or Thymosin Alpha-1?: The highest available evidence level is "Studio sull'uomo" for Thymalin and "RCT sull'uomo" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Thymalin and Thymosin Alpha-1 in Germany and the United States?: Germania: Thymalin — Non approvato, Thymosin Alpha-1 — Non approvato. Stati Uniti: Thymalin — Non approvato, Thymosin Alpha-1 — Non approvato. These are factual summaries with source and review date on the individual pages.

Country

Thymalin

Thymosin Alpha-1

Germania

Non approvato

—

Su prescrizione

—

Stati Uniti

Non approvato

Frequently asked questions

What is the difference between Thymalin and Thymosin Alpha-1?

Thymalin is classified as "Guarigione", while Thymosin Alpha-1 is classified as "Guarigione". Thymalin: Complex of low-molecular polypeptides extracted from calf thymus. Approved in Russia since the 1970s as an immunomodulator. The exact composition is not standardised like a synthetic single peptide; Western controlled studies are largely absent. Thymosin Alpha-1: Synthetic 28-amino-acid peptide identical to a naturally occurring thymus peptide. Approved as Zadaxin in more than 30 countries (not US/EU) for hepatitis B treatment and as an immunomodulator. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Thymalin or Thymosin Alpha-1?

The highest available evidence level is "Studio sull'uomo" for Thymalin and "RCT sull'uomo" for Thymosin Alpha-1. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Thymalin and Thymosin Alpha-1 in Germany and the United States?

Germania: Thymalin — Non approvato, Thymosin Alpha-1 — Non approvato. Stati Uniti: Thymalin — Non approvato, Thymosin Alpha-1 — Non approvato. These are factual summaries with source and review date on the individual pages.