Vergelijking

Buserelin vs. Selank

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

57982-77-1

129954-34-3

Molecuulmassa

1239.42 g/mol

751.85 g/mol

Halfwaardetijd

geen gegevens

0.3 h

Sequentie

geen gegevens

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Werkingsmechanisme

Buserelin

Buserelin is a potent GnRH agonist: after an initial stimulatory surge ('flare'), continuous receptor occupancy causes downregulation and thereby suppression of LH, FSH and the downstream sex hormones.

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Bewijsbasis

Hoogste bewijs

Humane RCT

Humane studie

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Buserelin	Selank
Duitsland	Op recept	Niet goedgekeurd
RU	—	Op recept
Verenigde Staten	Niet goedgekeurd	Niet goedgekeurd

Volledige vermeldingen

Buserelin

Volledige vermelding →

Selank

Volledige vermelding →

Frequently asked questions

What is the difference between Buserelin and Selank?: Buserelin is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Buserelin: Buserelin is a synthetic GnRH agonist (including as a nasal spray). It is used in endometriosis, hormone-dependent prostate cancer and assisted reproduction; approved in Europe (Suprefact), not in the US. Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Buserelin or Selank?: The highest available evidence level is "Humane RCT" for Buserelin and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Buserelin and Selank in Germany and the United States?: Duitsland: Buserelin — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Buserelin — Niet goedgekeurd, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.

Country

Buserelin

Selank

Duitsland

Op recept

Niet goedgekeurd

—

Op recept

Verenigde Staten

Niet goedgekeurd

Frequently asked questions

What is the difference between Buserelin and Selank?

Buserelin is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Buserelin: Buserelin is a synthetic GnRH agonist (including as a nasal spray). It is used in endometriosis, hormone-dependent prostate cancer and assisted reproduction; approved in Europe (Suprefact), not in the US. Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Buserelin or Selank?

The highest available evidence level is "Humane RCT" for Buserelin and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Buserelin and Selank in Germany and the United States?

Duitsland: Buserelin — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Buserelin — Niet goedgekeurd, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.