Vergelijking
Cetrorelix vs. Epitalon
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
120287-85-6
307297-39-8
Molecuulmassa
1431.06 g/mol
390.35 g/mol
Halfwaardetijd
geen gegevens
0.3 h
Sequentie
geen gegevens
Ala-Glu-Asp-GlyWerkingsmechanisme
Cetrorelix
Cetrorelix competitively and immediately blocks the pituitary GnRH receptor, rapidly suppressing LH and FSH release — without the initial hormone surge ('flare') of GnRH agonists.
Epitalon
Postulated mechanisms include modulation of gene expression in pinealocytes, telomerase activation (observed in cell culture studies) and influence on melatonin synthesis. A defined primary receptor is not established; the mechanistic basis rests on in-vitro and animal data from the Khavinson group.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane studie
Studies
0
4
waarvan bij mensen
0
1
Geregistreerde effecten
2
4
Openstaande tegenstrijdigheden
0
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Cetrorelix and Epitalon?
- Cetrorelix is classified as "Onderzoek (overig)", while Epitalon is classified as "Onderzoek (overig)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Epitalon: Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin (V. Khavinson, St. Petersburg). Investigated in the Russian research and anti-ageing context; Western controlled trials are largely absent. No medicines approval in EU or US. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Cetrorelix or Epitalon?
- The highest available evidence level is "Humane RCT" for Cetrorelix and "Humane studie" for Epitalon. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Cetrorelix and Epitalon in Germany and the United States?
- Duitsland: Cetrorelix — Op recept, Epitalon — Niet goedgekeurd. Verenigde Staten: Cetrorelix — Op recept, Epitalon — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.