Vergelijking

Cetrorelix vs. Histrelin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

120287-85-6

220810-26-4

Molecuulmassa

1431.06 g/mol

1323.52 g/mol

Halfwaardetijd

geen gegevens

Sequentie

geen gegevens

Werkingsmechanisme

Cetrorelix

Cetrorelix competitively and immediately blocks the pituitary GnRH receptor, rapidly suppressing LH and FSH release — without the initial hormone surge ('flare') of GnRH agonists.

Histrelin

Continuous GnRH-agonist stimulation downregulates and desensitises the pituitary GnRH receptors — after the initial rise, LH, FSH and the sex hormones fall persistently.

Bewijsbasis

Hoogste bewijs

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Cetrorelix	Histrelin
Duitsland	Op recept	Op recept
Verenigde Staten	Op recept	Op recept

Volledige vermeldingen

Cetrorelix

Volledige vermelding →

Histrelin

Volledige vermelding →

Frequently asked questions

What is the difference between Cetrorelix and Histrelin?: Cetrorelix is classified as "Onderzoek (overig)", while Histrelin is classified as "Onderzoek (overig)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Histrelin: Histrelin is a nonapeptide GnRH agonist delivered as a once-yearly implant. Approved for central precocious puberty in children (Supprelin LA) and advanced prostate cancer (Vantas). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Cetrorelix or Histrelin?: The highest available evidence level is "Humane RCT" for Cetrorelix and "Humane RCT" for Histrelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Cetrorelix and Histrelin in Germany and the United States?: Duitsland: Cetrorelix — Op recept, Histrelin — Op recept. Verenigde Staten: Cetrorelix — Op recept, Histrelin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Cetrorelix

Histrelin

Duitsland

Op recept

Verenigde Staten

Op recept

Frequently asked questions

What is the difference between Cetrorelix and Histrelin?

Cetrorelix is classified as "Onderzoek (overig)", while Histrelin is classified as "Onderzoek (overig)". Cetrorelix: Cetrorelix is a synthetic decapeptide and GnRH antagonist. It is used in assisted reproduction (IVF) to prevent a premature LH surge during controlled ovarian stimulation. Histrelin: Histrelin is a nonapeptide GnRH agonist delivered as a once-yearly implant. Approved for central precocious puberty in children (Supprelin LA) and advanced prostate cancer (Vantas). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Cetrorelix or Histrelin?

The highest available evidence level is "Humane RCT" for Cetrorelix and "Humane RCT" for Histrelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Cetrorelix and Histrelin in Germany and the United States?

Duitsland: Cetrorelix — Op recept, Histrelin — Op recept. Verenigde Staten: Cetrorelix — Op recept, Histrelin — Op recept. These are factual summaries with source and review date on the individual pages.