Vergelijking
Enfuvirtid vs. Selank
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
159519-65-0
129954-34-3
Molecuulmassa
4491.88 g/mol
751.85 g/mol
Halfwaardetijd
geen gegevens
0.3 h
Sequentie
geen gegevens
Thr-Lys-Pro-Arg-Pro-Gly-ProWerkingsmechanisme
Enfuvirtid
Enfuvirtide binds the first heptad-repeat region (HR1) of the gp41 subunit of the HIV envelope protein. This prevents the conformational change required for fusion of the viral and cell membranes — the virus cannot enter the cell.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane studie
Studies
1
4
waarvan bij mensen
1
2
Geregistreerde effecten
2
3
Openstaande tegenstrijdigheden
0
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Enfuvirtid and Selank?
- Enfuvirtid is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Enfuvirtid: Enfuvirtide is a synthetic 36-amino-acid peptide and the first HIV-1 fusion inhibitor. It binds the HR1 region of the viral envelope protein gp41, blocking viral entry into the cell. Approved for treatment-experienced HIV patients. Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Enfuvirtid or Selank?
- The highest available evidence level is "Humane RCT" for Enfuvirtid and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Enfuvirtid and Selank in Germany and the United States?
- Duitsland: Enfuvirtid — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Enfuvirtid — Op recept, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.