Vergelijking

GHRP-2 vs. Sermorelin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Groei

CAS-nr.

158861-67-7

86168-78-7

Molecuulmassa

817.93 g/mol

3358 g/mol

Halfwaardetijd

0.5 h

0.2 h

Sequentie

D-Ala-D-2-Naphthyl-Ala-Ala-Trp-D-Phe-Lys-NH2

YADAIFTNSYRKVLGQLSARKLLQDIMSR

Werkingsmechanisme

GHRP-2

GHRP-2 binds with high affinity to the GH secretagogue receptor (GHSR-1a) in the pituitary and hypothalamus. Activation leads to rapid release of pulsatile growth hormone. Unlike GHRH, GHRP-2 acts via a separate pathway and can be combined synergistically with GHRH to elicit maximal GH responses in provocation tests.

Sermorelin

Synthetic analogue of the first 29 amino acids of human growth-hormone-releasing hormone (GHRH). Stimulates pulsatile endogenous growth-hormone secretion from the pituitary via the GHRH receptor. Very short plasma half-life — pharmacodynamic effect lasts several hours nevertheless.

Bewijsbasis

Hoogste bewijs

Humane studie

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	GHRP-2	Sermorelin
Duitsland	Niet goedgekeurd	Niet goedgekeurd
JP	Op recept	—
Verenigde Staten	Niet goedgekeurd	Alleen onderzoek

Volledige vermeldingen

GHRP-2

Volledige vermelding →

Sermorelin

Volledige vermelding →

Frequently asked questions

What is the difference between GHRP-2 and Sermorelin?: GHRP-2 is classified as "Groei", while Sermorelin is classified as "Groei". GHRP-2: Synthetic hexapeptide of the GH secretagogue family. Approved in Japan as GHRP Kaken as a diagnostic test for GH deficiency. Not available as a medicine outside Japan. Sermorelin: Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Formerly FDA-approved as Geref Diagnostic, now withdrawn in many markets — compounding and research use dominate. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, GHRP-2 or Sermorelin?: The highest available evidence level is "Humane studie" for GHRP-2 and "Humane RCT" for Sermorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of GHRP-2 and Sermorelin in Germany and the United States?: Duitsland: GHRP-2 — Niet goedgekeurd, Sermorelin — Niet goedgekeurd. Verenigde Staten: GHRP-2 — Niet goedgekeurd, Sermorelin — Alleen onderzoek. These are factual summaries with source and review date on the individual pages.

Country

GHRP-2

Sermorelin

Duitsland

Niet goedgekeurd

Op recept

—

Verenigde Staten

Niet goedgekeurd

Alleen onderzoek

Frequently asked questions

What is the difference between GHRP-2 and Sermorelin?

GHRP-2 is classified as "Groei", while Sermorelin is classified as "Groei". GHRP-2: Synthetic hexapeptide of the GH secretagogue family. Approved in Japan as GHRP Kaken as a diagnostic test for GH deficiency. Not available as a medicine outside Japan. Sermorelin: Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Formerly FDA-approved as Geref Diagnostic, now withdrawn in many markets — compounding and research use dominate. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, GHRP-2 or Sermorelin?

The highest available evidence level is "Humane studie" for GHRP-2 and "Humane RCT" for Sermorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of GHRP-2 and Sermorelin in Germany and the United States?

Duitsland: GHRP-2 — Niet goedgekeurd, Sermorelin — Niet goedgekeurd. Verenigde Staten: GHRP-2 — Niet goedgekeurd, Sermorelin — Alleen onderzoek. These are factual summaries with source and review date on the individual pages.