Vergelijking
Sekretin vs. Selank
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
geen gegevens
129954-34-3
Molecuulmassa
3055.5 g/mol
751.85 g/mol
Halfwaardetijd
geen gegevens
0.3 h
Sequentie
geen gegevens
Thr-Lys-Pro-Arg-Pro-Gly-ProWerkingsmechanisme
Sekretin
Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Bewijsbasis
Hoogste bewijs
Humane studie
Humane studie
Studies
0
4
waarvan bij mensen
0
2
Geregistreerde effecten
2
3
Openstaande tegenstrijdigheden
0
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Sekretin and Selank?
- Sekretin is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Sekretin or Selank?
- The highest available evidence level is "Humane studie" for Sekretin and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Sekretin and Selank in Germany and the United States?
- Duitsland: Sekretin — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Sekretin — Op recept, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.