Сравнение
Carbetocin vs. Sincalide
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
37025-55-1
25126-32-3
Молекулярная масса
нет данных
1143.29 g/mol
Период полувыведения
0.67 h
нет данных
Последовательность
нет данных
Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2Механизм действия
Carbetocin
Carbetocin is an oxytocin receptor agonist with prolonged duration. It triggers a sustained contraction of the uterus after birth, preventing atonic hemorrhage — unlike oxytocin, without a multi-hour infusion.
Sincalide
Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).
Доказательная база
Наивысшая доказательность
РКИ на людях
Исследование на людях
Исследования
1
0
из них на людях
1
0
Зафиксированные эффекты
2
1
Открытые противоречия
0
0
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Carbetocin and Sincalide?
- Carbetocin is classified as "Исследования (прочее)", while Sincalide is classified as "Исследования (прочее)". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Carbetocin or Sincalide?
- The highest available evidence level is "РКИ на людях" for Carbetocin and "Исследование на людях" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Carbetocin and Sincalide in Germany and the United States?
- Германия: Carbetocin — Рецептурный, Sincalide — Неясно. США: Carbetocin — Не одобрено, Sincalide — Рецептурный. These are factual summaries with source and review date on the individual pages.