Vergelijking

Carbetocin vs. Sincalide

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

37025-55-1

25126-32-3

Molecuulmassa

geen gegevens

1143.29 g/mol

Halfwaardetijd

0.67 h

geen gegevens

Sequentie

geen gegevens

Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

Werkingsmechanisme

Carbetocin

Carbetocin is an oxytocin receptor agonist with prolonged duration. It triggers a sustained contraction of the uterus after birth, preventing atonic hemorrhage — unlike oxytocin, without a multi-hour infusion.

Sincalide

Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).

Bewijsbasis

Hoogste bewijs

Humane RCT

Humane studie

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Carbetocin	Sincalide
Duitsland	Op recept	Onduidelijk
Verenigde Staten	Niet goedgekeurd	Op recept

Volledige vermeldingen

Carbetocin

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Sincalide

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Frequently asked questions

What is the difference between Carbetocin and Sincalide?: Carbetocin is classified as "Onderzoek (overig)", while Sincalide is classified as "Onderzoek (overig)". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Carbetocin or Sincalide?: The highest available evidence level is "Humane RCT" for Carbetocin and "Humane studie" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Carbetocin and Sincalide in Germany and the United States?: Duitsland: Carbetocin — Op recept, Sincalide — Onduidelijk. Verenigde Staten: Carbetocin — Niet goedgekeurd, Sincalide — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Carbetocin

Sincalide

Duitsland

Op recept

Onduidelijk

Verenigde Staten

Niet goedgekeurd

Op recept

Frequently asked questions

What is the difference between Carbetocin and Sincalide?

Carbetocin is classified as "Onderzoek (overig)", while Sincalide is classified as "Onderzoek (overig)". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Carbetocin or Sincalide?

The highest available evidence level is "Humane RCT" for Carbetocin and "Humane studie" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Carbetocin and Sincalide in Germany and the United States?

Duitsland: Carbetocin — Op recept, Sincalide — Onduidelijk. Verenigde Staten: Carbetocin — Niet goedgekeurd, Sincalide — Op recept. These are factual summaries with source and review date on the individual pages.