Confronto
Carbetocin vs. Sincalide
Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.
Identità
Categoria
Ricerca (altro)
Ricerca (altro)
N. CAS
37025-55-1
25126-32-3
Peso molecolare
nessun dato
1143.29 g/mol
Emivita
0.67 h
nessun dato
Sequenza
nessun dato
Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2Meccanismo d'azione
Carbetocin
Carbetocin is an oxytocin receptor agonist with prolonged duration. It triggers a sustained contraction of the uterus after birth, preventing atonic hemorrhage — unlike oxytocin, without a multi-hour infusion.
Sincalide
Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).
Base di evidenze
Evidenza più alta
RCT sull'uomo
Studio sull'uomo
Studi
1
0
di cui sull'uomo
1
0
Effetti registrati
2
1
Contraddizioni aperte
0
0
Eventi avversi documentati
1
1
Stato legale
Voci complete
Frequently asked questions
- What is the difference between Carbetocin and Sincalide?
- Carbetocin is classified as "Ricerca (altro)", while Sincalide is classified as "Ricerca (altro)". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Carbetocin or Sincalide?
- The highest available evidence level is "RCT sull'uomo" for Carbetocin and "Studio sull'uomo" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Carbetocin and Sincalide in Germany and the United States?
- Germania: Carbetocin — Su prescrizione, Sincalide — Non chiaro. Stati Uniti: Carbetocin — Non approvato, Sincalide — Su prescrizione. These are factual summaries with source and review date on the individual pages.