Сравнение
CJC-1295 vs. MGF (Mechano Growth Factor)
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Рост
Рост
Номер CAS
нет данных
12-Aminosäuren-C-terminales E-Domänen-Peptid (Sequenz nicht standardisiert)
Молекулярная масса
3647.3 g/mol
2867.2 g/mol
Период полувыведения
144 h
0.1 h
Последовательность
YADAIFTNSYRKVLGQLSARKLLQDIMSR-DACYQPPSTNKNTKSQRRKGSTFEERKМеханизм действия
CJC-1295
Synthetic analogue of growth-hormone-releasing hormone (GHRH), modified for extended half-life via a Drug Affinity Complex (DAC) binding to albumin. Acts on the pituitary GHRH receptor and stimulates endogenous growth-hormone release.
MGF (Mechano Growth Factor)
The IGF-1 gene produces multiple isoforms by alternative splicing. IGF-1Ec is upregulated after mechanical muscle loading; the C-terminal E-domain is cleaved from the mature IGF-1 protein and appears to have independent effects on satellite cells. The exact receptor binding of the E-domain is not established; a classical IGF-1R effect is unlikely since mature IGF-1 is responsible. In cell-culture studies, stimulation of myoblast proliferation and differentiation has been observed.
Доказательная база
Наивысшая доказательность
Исследование на людях
Модель на животных
Исследования
4
4
из них на людях
3
0
Зафиксированные эффекты
3
3
Открытые противоречия
1
1
Задокументированные нежелательные явления
3
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between CJC-1295 and MGF (Mechano Growth Factor)?
- CJC-1295 is classified as "Рост", while MGF (Mechano Growth Factor) is classified as "Рост". CJC-1295: Long-acting synthetic GHRH analogue modified for albumin binding (DAC). Stimulates endogenous growth-hormone release. Pharmacodynamic effect established in small human studies; clinical endpoint trials are missing. MGF (Mechano Growth Factor): Synthetic peptide corresponding to the C-terminal E-domain of the IGF-1 splice variant IGF-1Ec. Described in preclinical studies as a 'mechano-induced' skeletal muscle repair factor. No marketing approval; clinical use largely confined to the black market. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, CJC-1295 or MGF (Mechano Growth Factor)?
- The highest available evidence level is "Исследование на людях" for CJC-1295 and "Модель на животных" for MGF (Mechano Growth Factor). A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of CJC-1295 and MGF (Mechano Growth Factor) in Germany and the United States?
- Германия: CJC-1295 — Не одобрено, MGF (Mechano Growth Factor) — Не одобрено. США: CJC-1295 — Только для исследований, MGF (Mechano Growth Factor) — Не одобрено. These are factual summaries with source and review date on the individual pages.