Сравнение
Hexarelin vs. Ipamorelin
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Рост
Рост
Номер CAS
140703-51-1
170851-70-4
Молекулярная масса
887.05 g/mol
711.86 g/mol
Период полувыведения
0.9 h
2 h
Последовательность
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2Aib-His-D-2-Nal-D-Phe-Lys-NH2Механизм действия
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
Ipamorelin
Ipamorelin is a selective agonist at the GH secretagogue receptor (GHSR-1a). Compared to GHRP-2 and GHRP-6 its selectivity for the growth-hormone axis is higher; ACTH, cortisol and prolactin are not significantly stimulated in clinical studies. This selectivity was the main reason for its development over older GHRPs.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
4
4
из них на людях
3
3
Зафиксированные эффекты
3
3
Открытые противоречия
0
1
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Hexarelin and Ipamorelin?
- Hexarelin is classified as "Рост", while Ipamorelin is classified as "Рост". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. Ipamorelin: Synthetic pentapeptide and selective growth-hormone secretagogue. Developed at Novo Nordisk in the 1990s as a pentapeptide GHRP successor; clinical development was discontinued after phase 2 (post-operative ileus). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Hexarelin or Ipamorelin?
- The highest available evidence level is "Исследование на людях" for Hexarelin and "РКИ на людях" for Ipamorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Hexarelin and Ipamorelin in Germany and the United States?
- Германия: Hexarelin — Не одобрено, Ipamorelin — Не одобрено. США: Hexarelin — Не одобрено, Ipamorelin — Не одобрено. These are factual summaries with source and review date on the individual pages.