Сравнение
Hexarelin vs. Sermorelin
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Рост
Рост
Номер CAS
140703-51-1
86168-78-7
Молекулярная масса
887.05 g/mol
3358 g/mol
Период полувыведения
0.9 h
0.2 h
Последовательность
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2YADAIFTNSYRKVLGQLSARKLLQDIMSRМеханизм действия
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
Sermorelin
Synthetic analogue of the first 29 amino acids of human growth-hormone-releasing hormone (GHRH). Stimulates pulsatile endogenous growth-hormone secretion from the pituitary via the GHRH receptor. Very short plasma half-life — pharmacodynamic effect lasts several hours nevertheless.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
4
5
из них на людях
3
3
Зафиксированные эффекты
3
3
Открытые противоречия
0
1
Задокументированные нежелательные явления
1
3
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Hexarelin and Sermorelin?
- Hexarelin is classified as "Рост", while Sermorelin is classified as "Рост". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. Sermorelin: Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Formerly FDA-approved as Geref Diagnostic, now withdrawn in many markets — compounding and research use dominate. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Hexarelin or Sermorelin?
- The highest available evidence level is "Исследование на людях" for Hexarelin and "РКИ на людях" for Sermorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Hexarelin and Sermorelin in Germany and the United States?
- Германия: Hexarelin — Не одобрено, Sermorelin — Не одобрено. США: Hexarelin — Не одобрено, Sermorelin — Только для исследований. These are factual summaries with source and review date on the individual pages.