Confronto

Hexarelin vs. Sermorelin

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Crescita

N. CAS

140703-51-1

86168-78-7

Peso molecolare

887.05 g/mol

3358 g/mol

Emivita

0.9 h

0.2 h

Sequenza

His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

YADAIFTNSYRKVLGQLSARKLLQDIMSR

Meccanismo d'azione

Hexarelin

Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.

Sermorelin

Synthetic analogue of the first 29 amino acids of human growth-hormone-releasing hormone (GHRH). Stimulates pulsatile endogenous growth-hormone secretion from the pituitary via the GHRH receptor. Very short plasma half-life — pharmacodynamic effect lasts several hours nevertheless.

Base di evidenze

Evidenza più alta

Studio sull'uomo

RCT sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Hexarelin	Sermorelin
Australia	Vietato	—
Germania	Non approvato	Non approvato
Stati Uniti	Non approvato	Solo ricerca

Voci complete

Frequently asked questions

What is the difference between Hexarelin and Sermorelin?: Hexarelin is classified as "Crescita", while Sermorelin is classified as "Crescita". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. Sermorelin: Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Formerly FDA-approved as Geref Diagnostic, now withdrawn in many markets — compounding and research use dominate. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Hexarelin or Sermorelin?: The highest available evidence level is "Studio sull'uomo" for Hexarelin and "RCT sull'uomo" for Sermorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Hexarelin and Sermorelin in Germany and the United States?: Germania: Hexarelin — Non approvato, Sermorelin — Non approvato. Stati Uniti: Hexarelin — Non approvato, Sermorelin — Solo ricerca. These are factual summaries with source and review date on the individual pages.

Country

Hexarelin

Sermorelin

Australia

Vietato

—

Germania

Non approvato

Stati Uniti

Non approvato

Solo ricerca

Frequently asked questions

What is the difference between Hexarelin and Sermorelin?

Hexarelin is classified as "Crescita", while Sermorelin is classified as "Crescita". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. Sermorelin: Synthetic analogue of the first 29 amino acids of human GHRH. Stimulates pulsatile growth-hormone secretion from the pituitary. Formerly FDA-approved as Geref Diagnostic, now withdrawn in many markets — compounding and research use dominate. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Hexarelin or Sermorelin?

The highest available evidence level is "Studio sull'uomo" for Hexarelin and "RCT sull'uomo" for Sermorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Hexarelin and Sermorelin in Germany and the United States?

Germania: Hexarelin — Non approvato, Sermorelin — Non approvato. Stati Uniti: Hexarelin — Non approvato, Sermorelin — Solo ricerca. These are factual summaries with source and review date on the individual pages.