Сравнение
Selank vs. Terlipressin
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
129954-34-3
14636-12-5
Молекулярная масса
751.85 g/mol
1227.37 g/mol
Период полувыведения
0.3 h
нет данных
Последовательность
Thr-Lys-Pro-Arg-Pro-Gly-Proнет данных
Механизм действия
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Terlipressin
Terlipressin is slowly converted in the body to lysine-vasopressin by cleavage of the three N-terminal glycyl residues (reservoir effect) and activates V1 receptors. The splanchnic vasoconstriction improves renal perfusion in hepatorenal syndrome.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
4
1
из них на людях
2
1
Зафиксированные эффекты
3
2
Открытые противоречия
1
0
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Selank and Terlipressin?
- Selank is classified as "Исследования (прочее)", while Terlipressin is classified as "Исследования (прочее)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Terlipressin?
- The highest available evidence level is "Исследование на людях" for Selank and "РКИ на людях" for Terlipressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Terlipressin in Germany and the United States?
- Германия: Selank — Не одобрено, Terlipressin — Рецептурный. США: Selank — Не одобрено, Terlipressin — Рецептурный. These are factual summaries with source and review date on the individual pages.