Vergelijking

Selank vs. Terlipressin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

129954-34-3

14636-12-5

Molecuulmassa

751.85 g/mol

1227.37 g/mol

Halfwaardetijd

0.3 h

geen gegevens

Sequentie

Thr-Lys-Pro-Arg-Pro-Gly-Pro

geen gegevens

Werkingsmechanisme

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Terlipressin

Terlipressin is slowly converted in the body to lysine-vasopressin by cleavage of the three N-terminal glycyl residues (reservoir effect) and activates V1 receptors. The splanchnic vasoconstriction improves renal perfusion in hepatorenal syndrome.

Bewijsbasis

Hoogste bewijs

Humane studie

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Selank	Terlipressin
Duitsland	Niet goedgekeurd	Op recept
RU	Op recept	—
Verenigde Staten	Niet goedgekeurd	Op recept

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Selank

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Terlipressin

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Frequently asked questions

What is the difference between Selank and Terlipressin?: Selank is classified as "Onderzoek (overig)", while Terlipressin is classified as "Onderzoek (overig)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Terlipressin?: The highest available evidence level is "Humane studie" for Selank and "Humane RCT" for Terlipressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Terlipressin in Germany and the United States?: Duitsland: Selank — Niet goedgekeurd, Terlipressin — Op recept. Verenigde Staten: Selank — Niet goedgekeurd, Terlipressin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Selank

Terlipressin

Duitsland

Niet goedgekeurd

Op recept

—

Verenigde Staten

Niet goedgekeurd

Op recept

Frequently asked questions

What is the difference between Selank and Terlipressin?

Selank is classified as "Onderzoek (overig)", while Terlipressin is classified as "Onderzoek (overig)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Terlipressin?

The highest available evidence level is "Humane studie" for Selank and "Humane RCT" for Terlipressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Terlipressin in Germany and the United States?

Duitsland: Selank — Niet goedgekeurd, Terlipressin — Op recept. Verenigde Staten: Selank — Niet goedgekeurd, Terlipressin — Op recept. These are factual summaries with source and review date on the individual pages.