Confronto

Selank vs. Terlipressin

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Ricerca (altro)

N. CAS

129954-34-3

14636-12-5

Peso molecolare

751.85 g/mol

1227.37 g/mol

Emivita

0.3 h

nessun dato

Sequenza

Thr-Lys-Pro-Arg-Pro-Gly-Pro

nessun dato

Meccanismo d'azione

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Terlipressin

Terlipressin is slowly converted in the body to lysine-vasopressin by cleavage of the three N-terminal glycyl residues (reservoir effect) and activates V1 receptors. The splanchnic vasoconstriction improves renal perfusion in hepatorenal syndrome.

Base di evidenze

Evidenza più alta

Studio sull'uomo

RCT sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Selank	Terlipressin
Germania	Non approvato	Su prescrizione
RU	Su prescrizione	—
Stati Uniti	Non approvato	Su prescrizione

Voci complete

Frequently asked questions

What is the difference between Selank and Terlipressin?: Selank is classified as "Ricerca (altro)", while Terlipressin is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Terlipressin?: The highest available evidence level is "Studio sull'uomo" for Selank and "RCT sull'uomo" for Terlipressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Terlipressin in Germany and the United States?: Germania: Selank — Non approvato, Terlipressin — Su prescrizione. Stati Uniti: Selank — Non approvato, Terlipressin — Su prescrizione. These are factual summaries with source and review date on the individual pages.

Country

Selank

Terlipressin

Germania

Non approvato

Su prescrizione

—

Stati Uniti

Non approvato

Su prescrizione

Frequently asked questions

What is the difference between Selank and Terlipressin?

Selank is classified as "Ricerca (altro)", while Terlipressin is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Terlipressin: Terlipressin is a 12-amino-acid vasopressin analog and prodrug of lysine-vasopressin. As a V1 receptor agonist it is vasoconstrictive and is approved for hepatorenal syndrome (FDA 2022, Terlivaz). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Terlipressin?

The highest available evidence level is "Studio sull'uomo" for Selank and "RCT sull'uomo" for Terlipressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Terlipressin in Germany and the United States?

Germania: Selank — Non approvato, Terlipressin — Su prescrizione. Stati Uniti: Selank — Non approvato, Terlipressin — Su prescrizione. These are factual summaries with source and review date on the individual pages.