Сравнение
Selank vs. Triptorelin
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Исследования (прочее)
Исследования (прочее)
Номер CAS
129954-34-3
57773-63-4
Молекулярная масса
751.85 g/mol
1311.45 g/mol
Период полувыведения
0.3 h
3 h
Последовательность
Thr-Lys-Pro-Arg-Pro-Gly-PropGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2Механизм действия
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Triptorelin
Triptorelin binds with high affinity to the GnRH receptor in the pituitary. After initial stimulation of LH and FSH secretion (flare phase, about 1-2 weeks), receptor desensitisation follows with consecutive gonadotropin suppression. This results in a reversible chemical castration: in men testosterone, in women oestrogen suppression to the postmenopausal range.
Доказательная база
Наивысшая доказательность
Исследование на людях
РКИ на людях
Исследования
4
4
из них на людях
2
4
Зафиксированные эффекты
3
3
Открытые противоречия
1
0
Задокументированные нежелательные явления
1
3
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Selank and Triptorelin?
- Selank is classified as "Исследования (прочее)", while Triptorelin is classified as "Исследования (прочее)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Triptorelin: Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since the 1980s for prostate cancer, endometriosis and precocious puberty. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Triptorelin?
- The highest available evidence level is "Исследование на людях" for Selank and "РКИ на людях" for Triptorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Triptorelin in Germany and the United States?
- Германия: Selank — Не одобрено, Triptorelin — Рецептурный. США: Selank — Не одобрено, Triptorelin — Рецептурный. These are factual summaries with source and review date on the individual pages.