Vergelijking
Selank vs. Triptorelin
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
129954-34-3
57773-63-4
Molecuulmassa
751.85 g/mol
1311.45 g/mol
Halfwaardetijd
0.3 h
3 h
Sequentie
Thr-Lys-Pro-Arg-Pro-Gly-PropGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2Werkingsmechanisme
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Triptorelin
Triptorelin binds with high affinity to the GnRH receptor in the pituitary. After initial stimulation of LH and FSH secretion (flare phase, about 1-2 weeks), receptor desensitisation follows with consecutive gonadotropin suppression. This results in a reversible chemical castration: in men testosterone, in women oestrogen suppression to the postmenopausal range.
Bewijsbasis
Hoogste bewijs
Humane studie
Humane RCT
Studies
4
4
waarvan bij mensen
2
4
Geregistreerde effecten
3
3
Openstaande tegenstrijdigheden
1
0
Gedocumenteerde bijwerkingen
1
3
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Selank and Triptorelin?
- Selank is classified as "Onderzoek (overig)", while Triptorelin is classified as "Onderzoek (overig)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Triptorelin: Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since the 1980s for prostate cancer, endometriosis and precocious puberty. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Triptorelin?
- The highest available evidence level is "Humane studie" for Selank and "Humane RCT" for Triptorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Triptorelin in Germany and the United States?
- Duitsland: Selank — Niet goedgekeurd, Triptorelin — Op recept. Verenigde Staten: Selank — Niet goedgekeurd, Triptorelin — Op recept. These are factual summaries with source and review date on the individual pages.