Confronto

Selank vs. Triptorelin

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Ricerca (altro)

N. CAS

129954-34-3

57773-63-4

Peso molecolare

751.85 g/mol

1311.45 g/mol

Emivita

0.3 h

3 h

Sequenza

Thr-Lys-Pro-Arg-Pro-Gly-Pro

pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2

Meccanismo d'azione

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Triptorelin

Triptorelin binds with high affinity to the GnRH receptor in the pituitary. After initial stimulation of LH and FSH secretion (flare phase, about 1-2 weeks), receptor desensitisation follows with consecutive gonadotropin suppression. This results in a reversible chemical castration: in men testosterone, in women oestrogen suppression to the postmenopausal range.

Base di evidenze

Evidenza più alta

Studio sull'uomo

RCT sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Selank	Triptorelin
Germania	Non approvato	Su prescrizione
RU	Su prescrizione	—
Stati Uniti	Non approvato	Su prescrizione

Voci complete

Frequently asked questions

What is the difference between Selank and Triptorelin?: Selank is classified as "Ricerca (altro)", while Triptorelin is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Triptorelin: Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since the 1980s for prostate cancer, endometriosis and precocious puberty. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Triptorelin?: The highest available evidence level is "Studio sull'uomo" for Selank and "RCT sull'uomo" for Triptorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Triptorelin in Germany and the United States?: Germania: Selank — Non approvato, Triptorelin — Su prescrizione. Stati Uniti: Selank — Non approvato, Triptorelin — Su prescrizione. These are factual summaries with source and review date on the individual pages.

Country

Selank

Triptorelin

Germania

Non approvato

Su prescrizione

—

Stati Uniti

Non approvato

Su prescrizione

Frequently asked questions

What is the difference between Selank and Triptorelin?

Selank is classified as "Ricerca (altro)", while Triptorelin is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Triptorelin: Synthetic decapeptide GnRH agonist with increased affinity over native gonadotropin-releasing hormone. FDA- and EMA-approved since the 1980s for prostate cancer, endometriosis and precocious puberty. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Triptorelin?

The highest available evidence level is "Studio sull'uomo" for Selank and "RCT sull'uomo" for Triptorelin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Triptorelin in Germany and the United States?

Germania: Selank — Non approvato, Triptorelin — Su prescrizione. Stati Uniti: Selank — Non approvato, Triptorelin — Su prescrizione. These are factual summaries with source and review date on the individual pages.