Confronto

Selank vs. Semax

Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.

Identità

Categoria

Ricerca (altro)

N. CAS

129954-34-3

80714-61-0

Peso molecolare

751.85 g/mol

813.92 g/mol

Emivita

0.3 h

Sequenza

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Met-Glu-His-Phe-Pro-Gly-Pro

Meccanismo d'azione

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Semax

Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.

Base di evidenze

Evidenza più alta

Studio sull'uomo

Studi

di cui sull'uomo

Effetti registrati

Contraddizioni aperte

Eventi avversi documentati

Stato legale

Country	Selank	Semax
Germania	Non approvato	Non approvato
RU	Su prescrizione	Su prescrizione
Stati Uniti	Non approvato	Non approvato

Voci complete

Frequently asked questions

What is the difference between Selank and Semax?: Selank is classified as "Ricerca (altro)", while Semax is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Selank or Semax?: The highest available evidence level is "Studio sull'uomo" for Selank and "Studio sull'uomo" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Selank and Semax in Germany and the United States?: Germania: Selank — Non approvato, Semax — Non approvato. Stati Uniti: Selank — Non approvato, Semax — Non approvato. These are factual summaries with source and review date on the individual pages.

Country

Selank

Semax

Germania

Non approvato

Su prescrizione

Stati Uniti

Non approvato

Frequently asked questions

What is the difference between Selank and Semax?

Selank is classified as "Ricerca (altro)", while Semax is classified as "Ricerca (altro)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Selank or Semax?

The highest available evidence level is "Studio sull'uomo" for Selank and "Studio sull'uomo" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Selank and Semax in Germany and the United States?

Germania: Selank — Non approvato, Semax — Non approvato. Stati Uniti: Selank — Non approvato, Semax — Non approvato. These are factual summaries with source and review date on the individual pages.