Vergelijking
Selank vs. Semax
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
129954-34-3
80714-61-0
Molecuulmassa
751.85 g/mol
813.92 g/mol
Halfwaardetijd
0.3 h
0.3 h
Sequentie
Thr-Lys-Pro-Arg-Pro-Gly-ProMet-Glu-His-Phe-Pro-Gly-ProWerkingsmechanisme
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Semax
Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.
Bewijsbasis
Hoogste bewijs
Humane studie
Humane studie
Studies
4
4
waarvan bij mensen
2
2
Geregistreerde effecten
3
3
Openstaande tegenstrijdigheden
1
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Selank and Semax?
- Selank is classified as "Onderzoek (overig)", while Semax is classified as "Onderzoek (overig)". Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Selank or Semax?
- The highest available evidence level is "Humane studie" for Selank and "Humane studie" for Semax. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Selank and Semax in Germany and the United States?
- Duitsland: Selank — Niet goedgekeurd, Semax — Niet goedgekeurd. Verenigde Staten: Selank — Niet goedgekeurd, Semax — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.