Vergelijking
Carbetocin vs. Sekretin
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
37025-55-1
geen gegevens
Molecuulmassa
geen gegevens
3055.5 g/mol
Halfwaardetijd
0.67 h
geen gegevens
Sequentie
geen gegevens
geen gegevens
Werkingsmechanisme
Carbetocin
Carbetocin is an oxytocin receptor agonist with prolonged duration. It triggers a sustained contraction of the uterus after birth, preventing atonic hemorrhage — unlike oxytocin, without a multi-hour infusion.
Sekretin
Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane studie
Studies
1
0
waarvan bij mensen
1
0
Geregistreerde effecten
2
2
Openstaande tegenstrijdigheden
0
0
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Carbetocin and Sekretin?
- Carbetocin is classified as "Onderzoek (overig)", while Sekretin is classified as "Onderzoek (overig)". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Carbetocin or Sekretin?
- The highest available evidence level is "Humane RCT" for Carbetocin and "Humane studie" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Carbetocin and Sekretin in Germany and the United States?
- Duitsland: Carbetocin — Op recept, Sekretin — Op recept. Verenigde Staten: Carbetocin — Niet goedgekeurd, Sekretin — Op recept. These are factual summaries with source and review date on the individual pages.