Comparison
Carbetocin vs. Sekretin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Research other
Research other
CAS no.
37025-55-1
no data
Molecular weight
no data
3055.5 g/mol
Half-life
0.67 h
no data
Sequence
no data
no data
Mechanism of action
Carbetocin
Carbetocin is an oxytocin receptor agonist with prolonged duration. It triggers a sustained contraction of the uterus after birth, preventing atonic hemorrhage — unlike oxytocin, without a multi-hour infusion.
Sekretin
Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.
Evidence base
Highest evidence
Human RCT
Human trial
Studies
1
0
of which in humans
1
0
Effects recorded
2
2
Open conflicts
0
0
Documented adverse events
1
1
Legal status
Full entries
Frequently asked questions
- What is the difference between Carbetocin and Sekretin?
- Carbetocin is classified as "Research other", while Sekretin is classified as "Research other". Carbetocin: Carbetocin is a long-acting synthetic oxytocin analog (half-life ~40 minutes). It prevents postpartum hemorrhage as a single injection. Approved in Canada and the UK among others, NOT in the US. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Carbetocin or Sekretin?
- The highest available evidence level is "Human RCT" for Carbetocin and "Human trial" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Carbetocin and Sekretin in Germany and the United States?
- Germany: Carbetocin — Prescription, Sekretin — Prescription. United States: Carbetocin — Unapproved, Sekretin — Prescription. These are factual summaries with source and review date on the individual pages.