Vergelijking

Epitalon vs. Icatibant

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

307297-39-8

138614-30-9

Molecuulmassa

390.35 g/mol

1304.52 g/mol

Halfwaardetijd

0.3 h

geen gegevens

Sequentie

Ala-Glu-Asp-Gly

geen gegevens

Werkingsmechanisme

Epitalon

Postulated mechanisms include modulation of gene expression in pinealocytes, telomerase activation (observed in cell culture studies) and influence on melatonin synthesis. A defined primary receptor is not established; the mechanistic basis rests on in-vitro and animal data from the Khavinson group.

Icatibant

Icatibant competitively blocks the bradykinin B2 receptor. Because bradykinin mediates the vascular permeability, swelling and pain typical of hereditary angioedema, the blockade interrupts the acute attack.

Bewijsbasis

Hoogste bewijs

Humane studie

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Epitalon	Icatibant
Duitsland	Niet goedgekeurd	Op recept
RU	Alleen onderzoek	—
Verenigde Staten	Niet goedgekeurd	Op recept

Volledige vermeldingen

Epitalon

Volledige vermelding →

Icatibant

Volledige vermelding →

Frequently asked questions

What is the difference between Epitalon and Icatibant?: Epitalon is classified as "Onderzoek (overig)", while Icatibant is classified as "Onderzoek (overig)". Epitalon: Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin (V. Khavinson, St. Petersburg). Investigated in the Russian research and anti-ageing context; Western controlled trials are largely absent. No medicines approval in EU or US. Icatibant: Icatibant is a synthetic decapeptide and selective antagonist of the bradykinin B2 receptor. It is approved to treat acute attacks of hereditary angioedema (HAE). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Epitalon or Icatibant?: The highest available evidence level is "Humane studie" for Epitalon and "Humane RCT" for Icatibant. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Epitalon and Icatibant in Germany and the United States?: Duitsland: Epitalon — Niet goedgekeurd, Icatibant — Op recept. Verenigde Staten: Epitalon — Niet goedgekeurd, Icatibant — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Epitalon

Icatibant

Duitsland

Niet goedgekeurd

Op recept

Alleen onderzoek

—

Verenigde Staten

Niet goedgekeurd

Op recept

Frequently asked questions

What is the difference between Epitalon and Icatibant?

Epitalon is classified as "Onderzoek (overig)", while Icatibant is classified as "Onderzoek (overig)". Epitalon: Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin (V. Khavinson, St. Petersburg). Investigated in the Russian research and anti-ageing context; Western controlled trials are largely absent. No medicines approval in EU or US. Icatibant: Icatibant is a synthetic decapeptide and selective antagonist of the bradykinin B2 receptor. It is approved to treat acute attacks of hereditary angioedema (HAE). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Epitalon or Icatibant?

The highest available evidence level is "Humane studie" for Epitalon and "Humane RCT" for Icatibant. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Epitalon and Icatibant in Germany and the United States?

Duitsland: Epitalon — Niet goedgekeurd, Icatibant — Op recept. Verenigde Staten: Epitalon — Niet goedgekeurd, Icatibant — Op recept. These are factual summaries with source and review date on the individual pages.