Vergelijking
Epitalon vs. Selank
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
307297-39-8
129954-34-3
Molecuulmassa
390.35 g/mol
751.85 g/mol
Halfwaardetijd
0.3 h
0.3 h
Sequentie
Ala-Glu-Asp-GlyThr-Lys-Pro-Arg-Pro-Gly-ProWerkingsmechanisme
Epitalon
Postulated mechanisms include modulation of gene expression in pinealocytes, telomerase activation (observed in cell culture studies) and influence on melatonin synthesis. A defined primary receptor is not established; the mechanistic basis rests on in-vitro and animal data from the Khavinson group.
Selank
Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.
Bewijsbasis
Hoogste bewijs
Humane studie
Humane studie
Studies
4
4
waarvan bij mensen
1
2
Geregistreerde effecten
4
3
Openstaande tegenstrijdigheden
1
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Epitalon and Selank?
- Epitalon is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Epitalon: Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal extract epithalamin (V. Khavinson, St. Petersburg). Investigated in the Russian research and anti-ageing context; Western controlled trials are largely absent. No medicines approval in EU or US. Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Epitalon or Selank?
- The highest available evidence level is "Humane studie" for Epitalon and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Epitalon and Selank in Germany and the United States?
- Duitsland: Epitalon — Niet goedgekeurd, Selank — Niet goedgekeurd. Verenigde Staten: Epitalon — Niet goedgekeurd, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.