Vergelijking

Icatibant vs. Selank

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

138614-30-9

129954-34-3

Molecuulmassa

1304.52 g/mol

751.85 g/mol

Halfwaardetijd

geen gegevens

0.3 h

Sequentie

geen gegevens

Thr-Lys-Pro-Arg-Pro-Gly-Pro

Werkingsmechanisme

Icatibant

Icatibant competitively blocks the bradykinin B2 receptor. Because bradykinin mediates the vascular permeability, swelling and pain typical of hereditary angioedema, the blockade interrupts the acute attack.

Selank

Selank is a glyproline-tuftsin analog. Proposed mechanisms include modulation of the GABAergic system, effects on serotonin bioavailability, and influence on enkephalinases. Animal studies show anxiolytic and neuroprotective markers; a clear receptor target is not established.

Bewijsbasis

Hoogste bewijs

Humane RCT

Humane studie

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Icatibant	Selank
Duitsland	Op recept	Niet goedgekeurd
RU	—	Op recept
Verenigde Staten	Op recept	Niet goedgekeurd

Volledige vermeldingen

Icatibant

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Selank

Volledige vermelding →

Frequently asked questions

What is the difference between Icatibant and Selank?: Icatibant is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Icatibant: Icatibant is a synthetic decapeptide and selective antagonist of the bradykinin B2 receptor. It is approved to treat acute attacks of hereditary angioedema (HAE). Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Icatibant or Selank?: The highest available evidence level is "Humane RCT" for Icatibant and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Icatibant and Selank in Germany and the United States?: Duitsland: Icatibant — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Icatibant — Op recept, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.

Country

Icatibant

Selank

Duitsland

Op recept

Niet goedgekeurd

—

Op recept

Verenigde Staten

Op recept

Niet goedgekeurd

Frequently asked questions

What is the difference between Icatibant and Selank?

Icatibant is classified as "Onderzoek (overig)", while Selank is classified as "Onderzoek (overig)". Icatibant: Icatibant is a synthetic decapeptide and selective antagonist of the bradykinin B2 receptor. It is approved to treat acute attacks of hereditary angioedema (HAE). Selank: Synthetic heptapeptide derived from natural tuftsin. Approved as an anxiolytic (Selank) in Russia and some CIS states. Western phase-3 trials are absent; efficacy assessment relies on Russian research literature. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Icatibant or Selank?

The highest available evidence level is "Humane RCT" for Icatibant and "Humane studie" for Selank. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Icatibant and Selank in Germany and the United States?

Duitsland: Icatibant — Op recept, Selank — Niet goedgekeurd. Verenigde Staten: Icatibant — Op recept, Selank — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.