Vergelijking
Lanreotid vs. Sekretin
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Onderzoek (overig)
Onderzoek (overig)
CAS-nr.
108736-35-2
geen gegevens
Molecuulmassa
1096.34 g/mol
3055.5 g/mol
Halfwaardetijd
geen gegevens
geen gegevens
Sequentie
geen gegevens
geen gegevens
Werkingsmechanisme
Lanreotid
Lanreotide activates somatostatin receptors (chiefly SSTR2, additionally SSTR5), thereby suppressing the release of growth hormone, IGF-1 and various gastrointestinal and neuroendocrine hormones. It is metabolically far more stable than natural somatostatin.
Sekretin
Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.
Bewijsbasis
Hoogste bewijs
Humane RCT
Humane studie
Studies
1
0
waarvan bij mensen
1
0
Geregistreerde effecten
2
2
Openstaande tegenstrijdigheden
1
0
Gedocumenteerde bijwerkingen
2
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Lanreotid and Sekretin?
- Lanreotid is classified as "Onderzoek (overig)", while Sekretin is classified as "Onderzoek (overig)". Lanreotid: Lanreotide is a synthetic cyclic octapeptide analog of somatostatin. It binds preferentially to the somatostatin receptors SSTR2 and SSTR5 and is approved for treating acromegaly and certain neuroendocrine tumours. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Lanreotid or Sekretin?
- The highest available evidence level is "Humane RCT" for Lanreotid and "Humane studie" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Lanreotid and Sekretin in Germany and the United States?
- Duitsland: Lanreotid — Op recept, Sekretin — Op recept. Verenigde Staten: Lanreotid — Op recept, Sekretin — Op recept. These are factual summaries with source and review date on the individual pages.