Comparison
Lanreotid vs. Sekretin
Two peptides side-by-side — identity, evidence base, legal status and known adverse events.
Identity
Category
Research other
Research other
CAS no.
108736-35-2
no data
Molecular weight
1096.34 g/mol
3055.5 g/mol
Half-life
no data
no data
Sequence
no data
no data
Mechanism of action
Lanreotid
Lanreotide activates somatostatin receptors (chiefly SSTR2, additionally SSTR5), thereby suppressing the release of growth hormone, IGF-1 and various gastrointestinal and neuroendocrine hormones. It is metabolically far more stable than natural somatostatin.
Sekretin
Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.
Evidence base
Highest evidence
Human RCT
Human trial
Studies
1
0
of which in humans
1
0
Effects recorded
2
2
Open conflicts
1
0
Documented adverse events
2
1
Legal status
Full entries
Frequently asked questions
- What is the difference between Lanreotid and Sekretin?
- Lanreotid is classified as "Research other", while Sekretin is classified as "Research other". Lanreotid: Lanreotide is a synthetic cyclic octapeptide analog of somatostatin. It binds preferentially to the somatostatin receptors SSTR2 and SSTR5 and is approved for treating acromegaly and certain neuroendocrine tumours. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Lanreotid or Sekretin?
- The highest available evidence level is "Human RCT" for Lanreotid and "Human trial" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Lanreotid and Sekretin in Germany and the United States?
- Germany: Lanreotid — Prescription, Sekretin — Prescription. United States: Lanreotid — Prescription, Sekretin — Prescription. These are factual summaries with source and review date on the individual pages.