Vergelijking

Oxytocin vs. Sekretin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

50-56-6

geen gegevens

Molecuulmassa

1007.19 g/mol

3055.5 g/mol

Halfwaardetijd

0.05 h

geen gegevens

Sequentie

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2

geen gegevens

Werkingsmechanisme

Oxytocin

Oxytocin is synthesised in the hypothalamus and released via the posterior pituitary. Peripherally it binds the oxytocin receptor, a G-protein-coupled receptor, and through the phospholipase-C cascade and calcium release triggers contraction of uterine smooth muscle and milk ejection — the pharmacological basis of the obstetric approval. Centrally, oxytocin acts as a neuromodulator and has been linked to social bonding, trust and modulation of stress and anxiety circuits. Its central effects in humans are mechanistically incompletely understood, particularly because it is unclear to what extent peripherally or intranasally administered oxytocin crosses the blood-brain barrier.

Sekretin

Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.

Bewijsbasis

Hoogste bewijs

Humane RCT

Humane studie

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Oxytocin	Sekretin
Duitsland	Op recept	Op recept
Verenigde Staten	Op recept	Op recept

Volledige vermeldingen

Oxytocin

Volledige vermelding →

Sekretin

Volledige vermelding →

Frequently asked questions

What is the difference between Oxytocin and Sekretin?: Oxytocin is classified as "Onderzoek (overig)", while Sekretin is classified as "Onderzoek (overig)". Oxytocin: Oxytocin is an endogenous nonapeptide hormone of the posterior pituitary. In synthetic form (Pitocin, Syntocinon) it has been approved for decades to induce and augment labour and to control postpartum uterine bleeding. Strictly separate from this is intranasal use to influence social behaviour, trust, anxiety or autism symptoms: this use is unapproved, purely experimental, and yields inconsistent and often negative results in controlled trials. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Oxytocin or Sekretin?: The highest available evidence level is "Humane RCT" for Oxytocin and "Humane studie" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Oxytocin and Sekretin in Germany and the United States?: Duitsland: Oxytocin — Op recept, Sekretin — Op recept. Verenigde Staten: Oxytocin — Op recept, Sekretin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Oxytocin

Sekretin

Duitsland

Op recept

Verenigde Staten

Op recept

Frequently asked questions

What is the difference between Oxytocin and Sekretin?

Oxytocin is classified as "Onderzoek (overig)", while Sekretin is classified as "Onderzoek (overig)". Oxytocin: Oxytocin is an endogenous nonapeptide hormone of the posterior pituitary. In synthetic form (Pitocin, Syntocinon) it has been approved for decades to induce and augment labour and to control postpartum uterine bleeding. Strictly separate from this is intranasal use to influence social behaviour, trust, anxiety or autism symptoms: this use is unapproved, purely experimental, and yields inconsistent and often negative results in controlled trials. Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Oxytocin or Sekretin?

The highest available evidence level is "Humane RCT" for Oxytocin and "Humane studie" for Sekretin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Oxytocin and Sekretin in Germany and the United States?

Duitsland: Oxytocin — Op recept, Sekretin — Op recept. Verenigde Staten: Oxytocin — Op recept, Sekretin — Op recept. These are factual summaries with source and review date on the individual pages.