Vergelijking

Bremelanotide vs. Vasopressin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

189691-06-3

geen gegevens

Molecuulmassa

1025.18 g/mol

1084.23 g/mol

Halfwaardetijd

2.7 h

geen gegevens

Sequentie

Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-OH

geen gegevens

Werkingsmechanisme

Bremelanotide

Bremelanotide is a cyclic peptide that binds non-selectively to melanocortin receptors (MC1R through MC5R) — with highest affinity at MC4R in the central nervous system. The precise role of MC4R activation in sexual behaviour is not fully understood; animal data show effects on hypothalamic circuits. Peripheral effects (blood pressure, hyperpigmentation) are attributed to MC1R/MC2R.

Vasopressin

Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.

Bewijsbasis

Hoogste bewijs

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Bremelanotide	Vasopressin
Australië	Beperkt	—
Duitsland	Niet goedgekeurd	Op recept
Verenigde Staten	Op recept	Op recept

Volledige vermeldingen

Bremelanotide

Volledige vermelding →

Vasopressin

Volledige vermelding →

Frequently asked questions

What is the difference between Bremelanotide and Vasopressin?: Bremelanotide is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Bremelanotide: Synthetic cyclic heptapeptide acting as a non-selective melanocortin-receptor agonist. FDA-approved in 2019 as Vyleesi for hypoactive sexual desire disorder (HSDD) in pre-menopausal women. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Bremelanotide or Vasopressin?: The highest available evidence level is "Humane RCT" for Bremelanotide and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Bremelanotide and Vasopressin in Germany and the United States?: Duitsland: Bremelanotide — Niet goedgekeurd, Vasopressin — Op recept. Verenigde Staten: Bremelanotide — Op recept, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Bremelanotide

Vasopressin

Australië

Beperkt

—

Duitsland

Niet goedgekeurd

Op recept

Verenigde Staten

Op recept

Frequently asked questions

What is the difference between Bremelanotide and Vasopressin?

Bremelanotide is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Bremelanotide: Synthetic cyclic heptapeptide acting as a non-selective melanocortin-receptor agonist. FDA-approved in 2019 as Vyleesi for hypoactive sexual desire disorder (HSDD) in pre-menopausal women. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Bremelanotide or Vasopressin?

The highest available evidence level is "Humane RCT" for Bremelanotide and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Bremelanotide and Vasopressin in Germany and the United States?

Duitsland: Bremelanotide — Niet goedgekeurd, Vasopressin — Op recept. Verenigde Staten: Bremelanotide — Op recept, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.