Vergelijking

Sekretin vs. Sincalide

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

geen gegevens

25126-32-3

Molecuulmassa

3055.5 g/mol

1143.29 g/mol

Halfwaardetijd

geen gegevens

Sequentie

geen gegevens

Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2

Werkingsmechanisme

Sekretin

Secretin binds the Gs-coupled secretin receptor (SCTR) on pancreatic duct cells, opens CFTR chloride channels and triggers secretion of bicarbonate-rich pancreatic fluid and bile flow.

Sincalide

Sincalide activates CCK receptors, triggering gallbladder contraction and pancreatic enzyme secretion. This effect is used diagnostically to measure the gallbladder ejection fraction (e.g. in HIDA scintigraphy).

Bewijsbasis

Hoogste bewijs

Humane studie

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Sekretin	Sincalide
Duitsland	Op recept	Onduidelijk
Verenigde Staten	Op recept	Op recept

Volledige vermeldingen

Sekretin

Volledige vermelding →

Sincalide

Volledige vermelding →

Frequently asked questions

What is the difference between Sekretin and Sincalide?: Sekretin is classified as "Onderzoek (overig)", while Sincalide is classified as "Onderzoek (overig)". Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Sekretin or Sincalide?: The highest available evidence level is "Humane studie" for Sekretin and "Humane studie" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Sekretin and Sincalide in Germany and the United States?: Duitsland: Sekretin — Op recept, Sincalide — Onduidelijk. Verenigde Staten: Sekretin — Op recept, Sincalide — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Sekretin

Sincalide

Duitsland

Op recept

Onduidelijk

Verenigde Staten

Op recept

Frequently asked questions

What is the difference between Sekretin and Sincalide?

Sekretin is classified as "Onderzoek (overig)", while Sincalide is classified as "Onderzoek (overig)". Sekretin: Secretin is a 27-amino-acid hormone that regulates pancreatic bicarbonate secretion. As ChiRhoStim it is FDA-approved as a diagnostic agent (pancreatic function test, gastrinoma test, secretin-enhanced MRCP). Sincalide: Sincalide is the synthetic C-terminal octapeptide of the hormone cholecystokinin (CCK-8). As Kinevac it is FDA-approved to stimulate gallbladder contraction for diagnostic imaging. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Sekretin or Sincalide?

The highest available evidence level is "Humane studie" for Sekretin and "Humane studie" for Sincalide. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Sekretin and Sincalide in Germany and the United States?

Duitsland: Sekretin — Op recept, Sincalide — Onduidelijk. Verenigde Staten: Sekretin — Op recept, Sincalide — Op recept. These are factual summaries with source and review date on the individual pages.