Vergelijking

Semax vs. Vasopressin

Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.

Identiteit

Categorie

Onderzoek (overig)

CAS-nr.

80714-61-0

geen gegevens

Molecuulmassa

813.92 g/mol

1084.23 g/mol

Halfwaardetijd

0.3 h

geen gegevens

Sequentie

Met-Glu-His-Phe-Pro-Gly-Pro

geen gegevens

Werkingsmechanisme

Semax

Semax is a tetracosactide fragment analog without hormonal activity at MC2R. Proposed mechanisms include elevation of BDNF and NGF in hippocampus and striatum (in animal models), modulation of dopamine metabolism, and neuroprotective effects via anti-apoptotic pathways. A clear primary receptor is not established.

Vasopressin

Vasopressin binds V1 receptors (vasoconstriction, raising vascular resistance) and V2 receptors (renal water reabsorption via aquaporin channels). This raises blood pressure and acts antidiuretically. Desmopressin is the V2-selective synthetic analog.

Bewijsbasis

Hoogste bewijs

Humane studie

Humane RCT

Studies

waarvan bij mensen

Geregistreerde effecten

Openstaande tegenstrijdigheden

Gedocumenteerde bijwerkingen

Juridische status

Country	Semax	Vasopressin
Duitsland	Niet goedgekeurd	Op recept
RU	Op recept	—
Verenigde Staten	Niet goedgekeurd	Op recept

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Semax

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Vasopressin

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Frequently asked questions

What is the difference between Semax and Vasopressin?: Semax is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
Which peptide is better supported by science, Semax or Vasopressin?: The highest available evidence level is "Humane studie" for Semax and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
What is the legal status of Semax and Vasopressin in Germany and the United States?: Duitsland: Semax — Niet goedgekeurd, Vasopressin — Op recept. Verenigde Staten: Semax — Niet goedgekeurd, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.

Country

Semax

Vasopressin

Duitsland

Niet goedgekeurd

Op recept

—

Verenigde Staten

Niet goedgekeurd

Op recept

Frequently asked questions

What is the difference between Semax and Vasopressin?

Semax is classified as "Onderzoek (overig)", while Vasopressin is classified as "Onderzoek (overig)". Semax: Synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10). Approved in Russia for ischaemic stroke, cognitive function and ADHD in children. Western phase-3 trials absent. Vasopressin: Vasopressin (arginine vasopressin, antidiuretic hormone/ADH) is a cyclic nonapeptide hormone that regulates water balance and vascular tone. As Vasostrict it is approved to raise blood pressure in vasodilatory shock. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.

Which peptide is better supported by science, Semax or Vasopressin?

The highest available evidence level is "Humane studie" for Semax and "Humane RCT" for Vasopressin. A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.

What is the legal status of Semax and Vasopressin in Germany and the United States?

Duitsland: Semax — Niet goedgekeurd, Vasopressin — Op recept. Verenigde Staten: Semax — Niet goedgekeurd, Vasopressin — Op recept. These are factual summaries with source and review date on the individual pages.