Сравнение
Hexarelin vs. MGF (Mechano Growth Factor)
Два пептида рядом — идентичность, доказательная база, правовой статус и известные нежелательные явления.
Идентичность
Категория
Рост
Рост
Номер CAS
140703-51-1
12-Aminosäuren-C-terminales E-Domänen-Peptid (Sequenz nicht standardisiert)
Молекулярная масса
887.05 g/mol
2867.2 g/mol
Период полувыведения
0.9 h
0.1 h
Последовательность
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2YQPPSTNKNTKSQRRKGSTFEERKМеханизм действия
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
MGF (Mechano Growth Factor)
The IGF-1 gene produces multiple isoforms by alternative splicing. IGF-1Ec is upregulated after mechanical muscle loading; the C-terminal E-domain is cleaved from the mature IGF-1 protein and appears to have independent effects on satellite cells. The exact receptor binding of the E-domain is not established; a classical IGF-1R effect is unlikely since mature IGF-1 is responsible. In cell-culture studies, stimulation of myoblast proliferation and differentiation has been observed.
Доказательная база
Наивысшая доказательность
Исследование на людях
Модель на животных
Исследования
4
4
из них на людях
3
0
Зафиксированные эффекты
3
3
Открытые противоречия
0
1
Задокументированные нежелательные явления
1
1
Правовой статус
Полные записи
Frequently asked questions
- What is the difference between Hexarelin and MGF (Mechano Growth Factor)?
- Hexarelin is classified as "Рост", while MGF (Mechano Growth Factor) is classified as "Рост". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. MGF (Mechano Growth Factor): Synthetic peptide corresponding to the C-terminal E-domain of the IGF-1 splice variant IGF-1Ec. Described in preclinical studies as a 'mechano-induced' skeletal muscle repair factor. No marketing approval; clinical use largely confined to the black market. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Hexarelin or MGF (Mechano Growth Factor)?
- The highest available evidence level is "Исследование на людях" for Hexarelin and "Модель на животных" for MGF (Mechano Growth Factor). A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Hexarelin and MGF (Mechano Growth Factor) in Germany and the United States?
- Германия: Hexarelin — Не одобрено, MGF (Mechano Growth Factor) — Не одобрено. США: Hexarelin — Не одобрено, MGF (Mechano Growth Factor) — Не одобрено. These are factual summaries with source and review date on the individual pages.