Vergelijking
Hexarelin vs. MGF (Mechano Growth Factor)
Twee peptiden naast elkaar — identiteit, bewijsbasis, juridische status en bekende bijwerkingen.
Identiteit
Categorie
Groei
Groei
CAS-nr.
140703-51-1
12-Aminosäuren-C-terminales E-Domänen-Peptid (Sequenz nicht standardisiert)
Molecuulmassa
887.05 g/mol
2867.2 g/mol
Halfwaardetijd
0.9 h
0.1 h
Sequentie
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2YQPPSTNKNTKSQRRKGSTFEERKWerkingsmechanisme
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
MGF (Mechano Growth Factor)
The IGF-1 gene produces multiple isoforms by alternative splicing. IGF-1Ec is upregulated after mechanical muscle loading; the C-terminal E-domain is cleaved from the mature IGF-1 protein and appears to have independent effects on satellite cells. The exact receptor binding of the E-domain is not established; a classical IGF-1R effect is unlikely since mature IGF-1 is responsible. In cell-culture studies, stimulation of myoblast proliferation and differentiation has been observed.
Bewijsbasis
Hoogste bewijs
Humane studie
Diermodel
Studies
4
4
waarvan bij mensen
3
0
Geregistreerde effecten
3
3
Openstaande tegenstrijdigheden
0
1
Gedocumenteerde bijwerkingen
1
1
Juridische status
Volledige vermeldingen
Frequently asked questions
- What is the difference between Hexarelin and MGF (Mechano Growth Factor)?
- Hexarelin is classified as "Groei", while MGF (Mechano Growth Factor) is classified as "Groei". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. MGF (Mechano Growth Factor): Synthetic peptide corresponding to the C-terminal E-domain of the IGF-1 splice variant IGF-1Ec. Described in preclinical studies as a 'mechano-induced' skeletal muscle repair factor. No marketing approval; clinical use largely confined to the black market. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Hexarelin or MGF (Mechano Growth Factor)?
- The highest available evidence level is "Humane studie" for Hexarelin and "Diermodel" for MGF (Mechano Growth Factor). A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Hexarelin and MGF (Mechano Growth Factor) in Germany and the United States?
- Duitsland: Hexarelin — Niet goedgekeurd, MGF (Mechano Growth Factor) — Niet goedgekeurd. Verenigde Staten: Hexarelin — Niet goedgekeurd, MGF (Mechano Growth Factor) — Niet goedgekeurd. These are factual summaries with source and review date on the individual pages.