Confronto
Hexarelin vs. MGF (Mechano Growth Factor)
Due peptidi a confronto — identità, base di evidenze, stato legale ed eventi avversi noti.
Identità
Categoria
Crescita
Crescita
N. CAS
140703-51-1
12-Aminosäuren-C-terminales E-Domänen-Peptid (Sequenz nicht standardisiert)
Peso molecolare
887.05 g/mol
2867.2 g/mol
Emivita
0.9 h
0.1 h
Sequenza
His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2YQPPSTNKNTKSQRRKGSTFEERKMeccanismo d'azione
Hexarelin
Hexarelin is a synthetic analog of the GHRP-6 family binding both the GH secretagogue receptor (GHSR-1a) and CD36. GHSR activation in the pituitary releases pulsatile growth hormone. Via CD36 in endothelium and myocardium, cardioprotective effects have been described in animal studies.
MGF (Mechano Growth Factor)
The IGF-1 gene produces multiple isoforms by alternative splicing. IGF-1Ec is upregulated after mechanical muscle loading; the C-terminal E-domain is cleaved from the mature IGF-1 protein and appears to have independent effects on satellite cells. The exact receptor binding of the E-domain is not established; a classical IGF-1R effect is unlikely since mature IGF-1 is responsible. In cell-culture studies, stimulation of myoblast proliferation and differentiation has been observed.
Base di evidenze
Evidenza più alta
Studio sull'uomo
Modello animale
Studi
4
4
di cui sull'uomo
3
0
Effetti registrati
3
3
Contraddizioni aperte
0
1
Eventi avversi documentati
1
1
Stato legale
Voci complete
Frequently asked questions
- What is the difference between Hexarelin and MGF (Mechano Growth Factor)?
- Hexarelin is classified as "Crescita", while MGF (Mechano Growth Factor) is classified as "Crescita". Hexarelin: Synthetic hexapeptide of the growth-hormone secretagogue (GHRP) family. In the 1990s investigated as an acromegaly diagnostic and for GH deficiency. Not an approved medicine. MGF (Mechano Growth Factor): Synthetic peptide corresponding to the C-terminal E-domain of the IGF-1 splice variant IGF-1Ec. Described in preclinical studies as a 'mechano-induced' skeletal muscle repair factor. No marketing approval; clinical use largely confined to the black market. This page contrasts both neutrally and source-based — with no usage or dosing recommendation.
- Which peptide is better supported by science, Hexarelin or MGF (Mechano Growth Factor)?
- The highest available evidence level is "Studio sull'uomo" for Hexarelin and "Modello animale" for MGF (Mechano Growth Factor). A higher evidence level means more robust data, but says nothing about suitability for an individual. The full body of evidence is on each peptide's own page.
- What is the legal status of Hexarelin and MGF (Mechano Growth Factor) in Germany and the United States?
- Germania: Hexarelin — Non approvato, MGF (Mechano Growth Factor) — Non approvato. Stati Uniti: Hexarelin — Non approvato, MGF (Mechano Growth Factor) — Non approvato. These are factual summaries with source and review date on the individual pages.